The best VTT for Star Trek: Adventures should be able to accommodate the STA 2d20 system, record key currencies of the game (Momentum, Threat, and Determination), and accurately reproduce iconic Star Trek settings and aesthetics to keep the universe consistent. 

These are the… surprisingly serious voyages of… Boaty McBoatface. I know. Stay with me. I love this roleplaying system—and I think you will too.